The real problems

As far as real 'problems' go, there are TWO actual, guaranteed-to-happen 'side effects' to replacing the factory radio, no matter which deck you have (RDS or not!).

1. There is no +12V switched wire in the factory radio wiring harness to use to turn your new deck on and off.

Why? Because GM switched to
Class 2 circuitry to turn the radio on and off, and to leave it on for 10 minutes until you open the driver's side door (you know what I'm talking about, right?) and do 'chime' the driver's speaker when some warning is going off.

There IS a constant +12V wire, as the factory deck always has power to save your presets and such. Either you or your installer will have to find a spot to tap into a switched ignition wire.

2. If you remove the factory deck, you lose the 'chimes' that tell you the lights are still on, or your key is in the ignition, or you're driving with the emergency brake on, etc, etc, etc.

No more chimes, ever. Which I think is not necessarily a bad thing... =)

Why? The factory radio uses
Class 2 signals to 'chime' the driver's door speaker. If you remove it, you lose the chimes. There isn't a separate GM chime module available either, so your only alternative is to relocate the factory deck, if you want to keep the chimes. If you don't like the chimes, then this is a no-brainer!