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   CLONING OF HUMANS:
   
THE UNTHINKABLE IS INEVITABLE

The proposal by American scientist Panayiotis Zavos and Italian physician Severino Antinori to clone human beings proves it is possible to be scientifically advanced and morally retarded at the same time. Who will look after the "mistakes" (The deformed babies that will inevitably result?) Will they be discarded like human garbage?
It is important to understand that it took more than 200 failed pregnancies in sheep before Dolly was successfully cloned. To create animal clones scientists have made hundreds of failed attempts to develop viable embryos. The failure rate in human cloning is likely to be even higher. Medical ethicists have posed the possibility of cruel failures in human cloning, where genetic abnormalities result in grotesque fetuses unable to survive outside the womb.


Antinori has sparked a furor in Italy by helping post-menopausal women (Some in their sixties!) become "granny moms." He has also pioneered a technique to help sterile men by "cultivating" their nascent sperm cells inside the testicles of mice.
The claim that human cloning is to help childless couples have children is an offensive pretext to justify the unjustifiable. If infertile couples want children so badly they should adopt one of the countless children waiting to be loved and cared for. Both the risk and cost would be minimal compared to cloned babies. In our world where 34,000 children die every day for a lack of food and basic medical care which could be provided for as little as one dollar a day per child, cloning a child at $200,000 a copy is morally outrageous.

Human cloning contravenes established legal, ethical and medical rules
Human cloning has already been outlawed by the European Convention on Human Rights and Biomedicine, covering not just the EU but all European states. The fact that Zavos and Antinori are prepared to go "offshore" proves the extent to which human cloning is regarded as professionally, medically and ethically unacceptable in most of the world.
Ethically, there is widespread international agreement that to clone a human being is wrong, because it gives scientists unprecedented control over someone else's complete genetic makeup, yet without any guarantees that such a lab baby will be physically and mentally healthy.
However, Pavos and Antinori do have the support of the Canadian cult known as Raelians who believe that humans are the result of genetic experimentation by a race of extraterrestrial beings called Elohim. But the Elohim in their wisdom have not shared their cloning technology with their Raelian followers.This seems to suggest the Elohim believe earthlings aren't ready for it....
Dr. Brigitte Boisselier, a chemical engineer by training and the scientific director of the Raelians, said in an interview with Reuters Health that she has hired a biochemist, a geneticist and a physician, "all US-trained," to carry out their cloning project. She said that the research is financed by a "$1 million investment from an American couple who lost their 10-month-old baby girl as the result of an accident."
Fifty young female Raelians have volunteered to be surrogate mothers--supplying eggs and providing womb space for embryos. Boisselier said the surrogate mother volunteers know "there is a possibility of miscarriage, but as Raelians they don't smoke or drink, they eat very healthy diets so we believe the miscarriage rate will be lower than might be expected. And, because we will be using the very best IVF (in vitro fertilization) technology, we think we will have a success rate similar to the success rate of IVF," she said. She predicted that "success rate" to be about 30% of implantations.
In the meantime orders for cloned babies at $200,000 per copy are pouring in to Raelian headquarters. What is the attraction apart from having a designer baby? Raelians say: "Once we can clone exact replicas of ourselves, the next step will be to transfer our memory and personality into our newly cloned brains, which will allow us to truly live forever. Since we will be able to remember all our past, we will be able to accumulate knowledge ad infinitum." Cult members apparently also believe that cloned versions of themselves will be able to better communicate with their extraterrestrial acquaintances.

BACK TO REALITY
Cloning is quite different from the randomness of identical twinning, where an embryo of unique and so far unknown genetic type spontaneously divides. Cloning takes the genetic material of an existing person and uses it as the basis of a new person. For the first time, a person would come into the world, however, who had had all their genes preordained by someone else. This is intrinsically wrong. We can "control" certain aspects of our upbringing, such as education and social influences, but we cannot change our genes.
It is medically unjustifiable and criminally irresponsible to attempt a technique on humans which is known frequently to cause deformities, large fetuses and premature deaths in sheep and cattle. There are also unknown psychological factors. For example, the genetic impact on personality.

Q. How would it be done?
A. The model is Dolly the sheep and although the technology has been applied to several animals, it is still highly underdeveloped and the mechanisms involved are poorly understood.
The scientists would remove the DNA from the nucleus of an egg cell taken from the mother. This DNA would then be replaced by the genetic material taken from one of the father's cells - perhaps a skin cell. A trigger would be applied to the egg cell that would then make it start to divide like any normal embryo. The mother would have it implanted in her womb in a procedure which is routinely performed in IVF clinics.
Q. What are the dangers?
A. Experience with the five mammal species that have been cloned so far indicates that Zavos and Antinori have almost no chance of success. The vast majority of pregnancies involving clones have gone very badly. In most of them, the clone has died and in almost all of them the lives of the mother and clone have been put at risk. In many cases, the clone grows abnormally large, often threatening to tear the womb that can also become swollen with fluid. Almost all clone pregnancies spontaneously abort.
Dolly the sheep, the first mammal clone, was the only success in 247 pregnancies. If a human clone is produced, the cost in human suffering and the trail of failures will be huge. Of the small number (little more than 1%) of animal clones that make it to term, most have severe abnormalities: malfunctioning livers, abnormal blood vessels and heart problems, underdeveloped lungs, diabetes, immune system deficiencies and possibly hidden genetic defects. Several cow clones had head deformities - none survived very long.
Q. What about screening for quality control?
A.
Screening for suitable embryos will not work. Normal babies are made from the joining of genes from sperm and egg. Genes are "imprinted" - a poorly understood process that avoids any genetic confusion between similar maternal and paternal genes. There is evidence that in clones this imprinting does not work properly. There is no way to screen embryos to detect this problem.
Q. What will happen if a clone grows up?
A. Very little is known about the long-term health of clones. There is some evidence that they may not live as long as conventional humans because of various health problems.
Q. Would the child be an exact copy of the genetic parent?
A.
No. On the genetic level, the clone would be 99.9% identical to its parent, but it would not be a complete copy, because there are some important genes that would be contributed by the egg donor. These genes reside outside the nucleus.
Also, the clone would be subject to different environmental factors and a different upbringing by his/her genetic parent. This could result in a changed appearance and personality. If the recent research on the human genome has taught us anything, it is that we are far more than just our genes.
Q. Is human cloning legal?
A.
In most countries that carry out advanced biomedical research human cloning is illegal. In less developed countries, including some that offer test-tube baby programs, there are no laws against it. So it is clear that the cloning of a human being is inevitable and much closer than most people think. What is not clear is the extent of the human cost that this procedure will exact.

For more information see Dr. Mercola's report: http://dr@mercola.com/2001/feb/10/human_clone.htm

The Raelian web site is:  http://dr@mercola.com/2001/feb/10/child_clone.htm

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