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||Prewritten queries into the peer-reviewed glutathione references show low levels of your body's most powerful healing agent is linked to most diseases and degenerative disorders and ALL age-related diseases.|
You can also enter glutathione AND lipid peroxidation or GSH AND oxidative stress in the search box. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi
Glutathione is crucial to our survival. Low levels invariably result in increased infection and inflammaiton, rising toxin load, degeneration, cell and mitochondrial damage and cell death. Obviously it's better to elevate glutathione (GSH) than not; the alternative is to accept rampant free radical cascades (oxidative stress), a long list of disorders and a failure to thrive, such as seen in the general deterioration associated with aging.
Raising cellular GSH levels has historically been difficult because GSH must be created within each cell by supplying the correct precursors. Both oral cysteine and glutathione that have been used for want of a better solution are broken down in the gut, enter the bloodstream and the cells with difficulty, and hardly increase cellular GSH. Cysteine at useful levels has known toxicity issues; similarly the toxic drug N-Acetyl cysteine (NAC) has been used but has known side effects and a half-life of only two hours. It is used primarily in emergencies to prevent the liver from liquefying in the event of acetaminophen overdose. NAC-induced glutathione levels often plunge to well below original values when the drug is withdrawn.
An undenatured (unbroken, uncooked) whey isolate is ideally suited to donate the GSH precursors, cysteine molecules bonded to another amino acid such as a cysteine=cysteine dipeptide called cystine. Bonded cysteine enters the blood and the cells readily to create glutathione. There is no toxicity and the glutathione levels do not fluctuate as much with this method.
The science is proven; there is a medically approved whey isolate for the purpose of increasing cellular glutathione, where 90% is needed. In the process it also builds muscle and reduces wasting due to HIV or cancer. It is also a recognised chemotherapeutic agent even on its own. The recommended dose is 40-60 grams daily. The cost at that dose is prohibitive however, and the science applies also to the less expensive products.
To further elaborate on the science, The FDA website states that undenatured whey isolate is the ideal GSH precursor. http://www.fda.gov/ohrms/dockets/ac/00/slides/3652s1_05/sld001.htm
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