Duncan Crow
Wholistic Consultant


Degenerative Disorder and Anti-Aging Protocol


My "whey-inulin-selenium protocol" is catching on in the health community; it forms part of a protocol that has worked in autoimmune and degenerative disorders for which there is no cure. A non-drug protocol, it improves the hallmark of degenerative illness, that being cellular impairment and low ATP production, to reduce the cell senescence and cell death that causes degeneration and wasting, shriveled, scarred organs, and the eventual death of the subject.



Reduce Your So-Called Age-Related Cofactors for Disease:
  1. Manufacture of the antioxidant glutathione drops with age, also depleted with free radical and toxin load, AKA oxidative stress, illness, inflammation, infection, etc.
  2. The immune system is impaired with age as the thymus gland shrinks, less recovery takes place and fewer white blood cells might be produced due to reduced growth hormone; immune response also drops with stress from any source such as nutritional deficiency, chronic infection, emotional stress, illness, electromagnetic pollution, free radicals/oxidative stress, drugs, leaky gut syndrome.
  3. A crucial anti-clotting enzyme plasmin drops with age, causing thick blood, reduced oxygen to the tissues, clots, inflammation, fibrosis in the internal organs; clotting also increases in illness, free radical damage/oxidative stress, and inflammation.
  4. Master growth hormones HGH and IGF-1 drop with age and also by carbohydrate loading that results in an insulin rise or othewise chronically high insulin levels.
The fact that we address all of these in a program would be of particular importance to elderly readers and to people whose levels have been induced to fall, resulting in disease.

Reduce Toxin Load:

Mitochondrial disorders, according to medical courses can be caused by toxin load when they are not inherited. The reason why they are often seen as age-related may be reduced to accumulation of enough toxin load and low enough oxygen delivery to cause symptoms. The causes of mitochondrial impairment may be many, but as you'll see all of these diseases are more likely just different manifestations of the same disorder. Anything that can impair mitochondrial production of ATP energy, for example unsaturated oils, as seen in this study, can result in degenerative disease or cancer. Toxin load unbalances biological function by attaching to and impairing or damaging the mitochondria and other cellular structures, which necessarily interferes with cellular function. Sometimes, as in cancer or fibromyalgia, a trigger mechanism may catalyse the event into becoming apparent where the body had previously been maintaining equilibrium AKA 'homeostasis' despite the toxin load.

Promote bile flow into the stool; bile is full of toxins that can be recirculated by the liver if bile flow is impaired. Liver and gallbladder flush (the olive oil, epsom salts and lemon juice one) every three weeks until there are no more hepatic stones .

Support the liver, the biggest user of the body's master detoxifier and antioxidant enzyme glutathione, as it's breaking down toxins, by giving it glutathione precursors in the form of cold-processed, undenatured whey (plus selenium). Glutathione is directly involved in mitochondrial ATP energy production and it is also the main protector of the mitochondria. It is also the main support for the immune response, which is of interest because several studies link chronic infection to accelerated degeneration. When glutathione levels are low, infection is stimulated, and when high, infection is reduced. Cold processed whey selection.

Feed the good bowel flora (probiotics) the inulin they require to outcompete pathogenic organisms in the gut. This will reduce toxin production in the gut that goes on 24 hours a day. As you'll see if you follow the research, eating probiotics neither provides the required actively fementing culture, nor does it provide the numbers needed to effect much change. Inulin references.

Reduce exposure to dietary toxins and free radicals including inflammation-causing food. Saturated oils cause much less free radical damage than unsaturated and especially, polyunsaturated. The oils analysis spreadsheet in the coconut oil references shows this difference, and well-referenced articles such as The Oiling Of America and The Cholesterol Myths, which are available online, addresses public misconceptions on dietary fats and cholesterol. Reducing carbohydrate loading will help facilitate normal metabolic function, and controlling/improving lymph and cell alkalinity should be a concern, following Nobel Prize work on oxygen carrying ability of alkaline tissues and cancer.

Further, one should know that all drugs cause a degree of cellular impairment and many even cause mitochondrial damage even on their own as in the case of the statin drug class of cholesterol medication. Obviously, removing toxins from the diet and environment would be an advantage.

Improve Nutritional Profile:

Cold processed whey supplies very bioavailable proteins that are much more easily absorbed than meat or eggs in addition to supplying glutathione precursors. It contains all of the essential amino acids and two of the glyconutients used in the healing process. Cold processed whey selection.

Regardless of whether there is a known bowel disturbance, bowel malabsorption is common due to gut acidity (pH) being incorrect. Inulin, a PREbiotic, supports correct bowel ecology and pH and results in better nutritient absorption. See the inulin references.

Macrominerals like magnesium and potassium are usually deficient, as are the b-vitamins and vitamin D, so should be supplemented in fairly generous quantities, for example a gram or more each of magnesium citrate and potassium chloride (No-Salt for example), 5,000 IU vitamin D, B-100 complex, and an extra gram or so of niacin or no-flush niacinamide.

Reduce Oxidative Stress Damage with Antioxidants and Anti-inflammatories:

These disorders are marked by low antioxidant values and high "oxidative stress", and dietary changes are important for reducing oxidative stress. While unsaturated oils are readily oxidized, saturated fats and coconut oil are low oxidizers that do not contribute to oxidative stress. Severely limiting carbohydrates and favouring fibrous vegetables, and taking an antioxidant program of at least vitamin A, C, E, D, and coenzyme Q-10, improves mitochondrial ATP production. Fish liver oil and cod liver oil that are used as an antiinflammatory also improve cell membrane function and integrity.

Promote the Healing and Vigor of a Young Adult with an HGH Approach:

A program of HGH increase supports regneration throughout the body, including the neural sheath, muscles and organs. Peer-reviewed research appears here.

The reason to use it, and an often overlooked part of many protocols particularly those for the elderly, is that healing and regeneration absolutely requires human growth hormone HGH levels to be adequate. Unfortunately, HGH production drops with age and at 60 years the body releases just half the HGH levels it does at 30. Thus the body's ability to repair is halved, later even quartered, with the obvious result of accumulating degeneration (damage) associated with aging and disease, as reported by FOX TV and ABC NEWS' 20/20 .

Youthful regeneration can be restored with prescription HGH shots; however the much less expensive patented supplement SomaLife gHP is preferred by many thousand doctors and their clients. This video on growth hormone therapy is also worth a look.

Educate and Improve Immune Response With Transfer Factor:

Degenerative illnesses are often called autoimmune disorders due to an overactive or inflammatory immune response, sometimes combined with underactive response to infection, as seen in Lupus. The immune system can be immunomodulated, or increased if too low and decreased if too high. Transfer factor is unique in that it not only is an immunomodulator, it increases the numbers of natural killer (NK) cells that don't need training, it also educates naive immune cells about a present or potential danger in your body and gives them a plan for action. This speeds up the recognition phase of a health threat and improves the immune system's ability to mount a counter-attack, thus making the duration of an illness shorter or avoiding the illness entirely. More information on Transfer Factor

Improve Circulation With Metabolic Enzymes:

Newer research backs up the nutritional approaches; this study Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, Alzheimer's disease, and Parkinson's disease says in part:
In the present review, we survey the literature to identify mitochondrial nutrients that can:
  1. protect mitochondrial enzymes and/or stimulate enzyme activity by elevating levels of substrates and cofactors;
  2. induce phase-2 enzymes [e.g. glutathione] to enhance antioxidant defenses;
  3. scavenge free radicals and prevent oxidant production in mitochondria, and
  4. repair mitochondrial membrane.

Nutritional approaches however are only as good as the delivery mechanism, your micro-circulation, and Pathological features of cerebral cortical capillaries are doubled in Alzheimer's disease and Parkinson's disease for example, (Acta Neuropathol (Berl). 2000 Oct) highlights the difficulty of servicing brain cells, and all the cells, by moving the nutrition, toxins, and oxygen that would normalise cellular function due to inflammation and damaged or blocked capilliaries. Cells with impaired function have impaired energy output; this is a precancerous condition that results in cell death as ATP production falls.

The key point here is that the body's only anti-clotting fibrinolytic enzyme Plasmin is reduced as one ages. Its effectiveness can also be reduced in response to chronic inflammation, disease, toxin load and depleted antioxidant pool.
Search PubMed


While fibrinolytic medications, unlike enzymes, can be used only infrequently because they carry bleeding risks, some metabolic enzymes are both fibrinolytic and anti-inflammatory, and because they work by a different mechanism they are virtually risk-free. Nattokinase for example is four times as potent as plasmin, and it improves natural plasmin release. Taken on an empty stomach, fibrinolytic enzymes reduce coagulation, dissolve clots, plaque, and fibrosis and can improve circulation, even, unlike the drugs, where blood flow is almost completely blocked. Obviously this improves nutrient and oxygen delivery and toxin removal; the result is improved cell metabolism and ATP generation, healing, growth, normal function etc. I've selected the enzymes blend BlockBuster All Clear as the best blend on the market; it carries a money-back guarantee that it'll work, so save your empty bottles. More information on metabolic enzymes.

Reduce Inflammatory Oils in Your Diet:

Alpha-linolenic acid (ALA), a component of Flaxseed oil, turns out to be a NON-essential omega-3 that was once thought to be a 'good' omega-3 oil. Research has revealed there is no known need at all for ALA except for a tiny amount of conversion to the real omega-3 essential fatty acids EPA/DHA. That abysmal performance has traditionally escaped the followers of Joanna Budwig and Udo Erasmus, but fatty acids expert Dr. Floyd Chilton fully explains it in his book Inflammation Nation. Chilton says (on page 97),
"I wish I could tell you that the (ALA) in flaxseed oil could replace wild fish as a rich source of EPA and DHA but the scientific literature simply does not support this contention. ...We do the conversion but very slowly, and we also eat a lot of fatty acids such as LA that 'compete' for enzymes that convert ALA to EPA and DHA, further limiting its conversion."
This competition for fatty acids uptake is most pronounced in the sad North American diet with its low EPA/DHA and higher omega-6 fatty acid intake due to corn, canola, soy, and safflower oil intake.

The fact that cell walls contain negligible ALA and are high EPA and DHA explains why one may need vastly more EPA and DHA than an ALA supplement can provide, and also explains why fish or krill oil supplements are more popular for inflammation than flax oil. Unlike ALA, EPA and DHA are essential to health and can reverse illnesses such as coronary heart disease, skin disorders and cancer. Wild salmon oil, even minimally refined oil, has almost no impurities. Inflammation can be further reduced by adding GLA or Borage oil if your EPA/DHA are attended to.

Essential fatty acids references show the anti-cancer properties of these oils.

Support ATP Production By Increasing Glutathione:

ATP energy generation is facilitated with glutathione, the master antioxidant, the precusors for which are plentiful in cold-processed whey. Unfortunately, glutathione levels are low in disease, a factor in the obvious accelerated aging that people go through when they are sick for awhile.

Ozone therapy is a valuable bio-oxidative therapy for increasing natural antioxidants including glutathione. By supporting aerobic processes it directly supports increased ATP energy production, and it also reduces blood clumping, improves capilliary flow, triggers beneficial antioxidant manufacture, oxidizes toxins, heavy metals and infections, and increases tissue oxygen. Ozone has been used to treat more than 254 diseases, including all of the infections, neurodegenerative illnesses and cancer. It is beyond the scope of this protocol to detail ozone therapy approaches but more information is available by contacting the author. You can even make your own ozonated olive oil. See also this primer, The Story of Ozone.




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