The Neo Physiocracy

H.H. Chartrand

April 2002

Exhibit 2

U.S. Army Biotechnology Development Areas, 2001

Development Areas

Biotechnology

Investment

Priority

Time

Frame

Commercial

Interest

Assay Analysis

Microfabrication/microfluidics

Affinity reagents

medium

medium

midterm

midterm

high

high

Detection Methods

Optical detectors

Detector arrays of affinity molecules; DNA chips; protein chips

low

medium

midterm

midterm

high

high

Protein-Based Devices

Optical-holographic high-density memories

Three-dimensional volumetric memories

Associative memories and processors

Artificial retinas

Pattern-recognition systems

Spatial light modulators

low

high

medium

low

medium

low

midterm

midterm

midterm

midterm

midterm

near term

medium

low

medium

low

low

low

Biocomputing

Biological models

DNA computers

medium

low

far term

far term

low

low

Biomolecular Hybrid Devices

DNA-based optical-signal processing

Bimolecular diodes

low

midterm

medium

Tissue Engineering

Cartilage repair and replacement

Neural bridging

Self-replicating systems

Stem cells

Synthetic biomaterials

Portable, artificial, assisting devices

medium

low

high

medium

low

low

midterm

far term

far term

far term

far term

far term

high

medium

medium

high

medium

high

Bioinspired & Hybrid Materials

Biologically produced materials

Biomineralization: organic/inorganic nanocomposites

Hierarchical systems: biocomposites

medium

low

medium

far term

far term

midterm

medium

medium

medium

Miniturization Technologies

Microreaction technologies

MEMS-based microfluidic systems

Biochip architectures

Biological nanotechnology

low

medium

low

medium

midterm

midterm

midterm

midterm

high

high

high

high

Functional Foods

Genetically engineered foods

Edible vaccines

low

medium

near term

midterm

high

medium

Biological Sources of Energy

Biological photovoltaics

medium

midterm

medium

Renewable Resources

Renewable fuels

Nonmedical specialty products based on engineered organisms

Ecological life-support systems

medium

low

low

midterm

near term

midterm

high

medium

low

Genoemics & Proteomics

Genomics data-gathering techniques

Gene-expression monitoring

Protein profiling

Biospectroscopics instruments; terahertz spectroscopy and analysis

Vaccine stratification by genomics and toxicogenomics

medium

medium

low

low

high

midterm

midterm

midterm

midterm

midterm

high

high

medium

high

high

Therapeutic Drugs & Vaccines

Small-scale vaccine production

Small-molecule and protein therapeutics

Genomics-based vaccine developments

Shock therapeutics

high

low

high

high

midterm

midterm

midterm

midterm

low

high

high

medium

Drug Delivery

Biocapsules

Implantable antidotes

Somatic gene therapy

low

medium

low

midterm

midterm

far term

high

medium

high

COBFAA, Opportunities in Biotechnology for Future Army Applications, National Academy Press, http://books.nap.edu/books/0309075556/html/index.html, 2001/06/20, p. 5.