Fetal Blood Sampling
Indications:
Confirm chromosomal mosaicism found on amniocentesis
Rapid karyotyping (48hrs)
Fetal blood grouping
Assess for fetal anemia, thrombocytopenia
Hemoglobinopathies
Hemophilia
Immunodeficiencies
Inborn errors of metabolism
US guidance risk 1% vs. fetoscope guidance risk 5%
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Tools
Confirm chromosomal mosaicism found on amniocentesis
Rapid karyotyping (48hrs)
Fetal blood grouping
Assess for fetal anemia, thrombocytopenia
Hemoglobinopathies
Hemophilia
Immunodeficiencies
Inborn errors of metabolism
US guidance risk 1% vs. fetoscope guidance risk 5%
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