| () |
| P450 | Function | Plant Species |
|---|---|---|
| CYP93C1 : | isoflavone synthase, IFS | soybean |
| CYP93C2 | isoflavone synthase, IFS | licorice |
| CYP93C | isoflavone synthase, IFS | lotus |
| CYP93C18 | isoflavone synthase, IFS | pea |
CYP93C1: isoflavone synthase (IFS), oxidation of 7,4'-dihyroxyflavanone (liquiritigenin) or 5,7,4'-trihydroxyflavanone (naringenin) to daidzein or genistein, respectively, soybean (Glycine max).
Jung W, Yu O, Lau SM, O'Keefe DP, Odell J, Fader G, McGonigle B (2000) Identification and expression of isoflavone synthase, the key enzyme for biosynthesis of isoflavones in legumes. Nature Biotech 18: 208-212. PubMed
CYP93C2: 2-hydroxyisoflavone synthase (IFS), isoflavonoid synthesis, licorice (Glycyrrhiza echinata).
1) Akashi T, Aoki T, Ayabe S (1999) Cloning and functional expression of a cytochrome P450 cDNA encoding 2-hydroxyisoflavanone synthase involved in biosynthesis of the isoflavonoid skeleton in licorice. Plant Physiol 121: 821-828. PubMed
2) Sawada Y, Kinoshita K, Akashi T, Aoki T, Ayabe SI (2002) Key amino acid residues required for aryl migration catalysed by the cytochrome P450 2-hydroxyisoflavanone synthase. Plant J 31: 555-564. PubMed
3) Ayabe S-I, Akashi T, Aoki T (2002) Cloning of cDNAs encoding P450s in flavonoid/isoflavonoid pathway from elicited leguminous cell cultures. Methods Enzymol 357: 360-369.
CYP93C: 2-hydroxyisoflavone synthase (IFS), isoflavonoid synthesis, lotus (Lotus japonicus).
Shimada N, Akashi T, Aoki T, Ayabe S (2000) Induction of isoflavonoid pathway in the model legume Lotus japonicus: molecular characterization of enzymes involved in phytoalexin biosynthesis. Plant Science 160: 37-47. PubMed
CYP93C18: isoflavone synthase, pea (Pisum sativum).
Cooper LD, Doss RP, Price R, Peterson K, Oliver JE (2005) Application of Bruchin B to pea pods results in the up-regulation of CYP93C18, a putative isoflavone synthase gene, and an increase in the level of pisatin, an isoflavone phytoalexin. J Exp Bot 56: 1229-1237. PubMed