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CYP93Bs


P450 Function Plant Species
CYP93B1 : flavone synthase II (FNS II, F2H), licodione synthase licorice
CYP93B2 flavone synthase II (FNS II, F2H) Gerbera
CYP93B3 flavone synthase II (FNS II, F2H) snapdragon, torenia
CYP93B4 flavone synthase II (FNS II, F2H) snapdragon, torenia
CYP93B6 flavone synthase II (FNS II, F2H) Chinese basil


CYP93B1:   (2S)-flavanone 2-hydroxylase (FNS II, F2H), licorice (Glycyrrhiza echinata).
1)  Otani K, Takahashi T, Furuya T, Ayabe S  (1994)  Licodione synthase, a cytochrome P450 monooxygenase catalyzing 2-hydroxylation of 5-deoxyflavanone, in cultured Glycyrrhiza echinata L. cells.  Plant Physiol 105: 1427-1432.  PubMed
2)  Akashi T, Aoki T, Ayabe S  (1998)  Identification of a cytochrome P450 cDNA encoding (2S)-flavanone 2-hydroxylase of licorice (Glycyrrhiza echinata L.; Fabaceae) which represents licodione synthase and flavone synthase II.  FEBS Lett 431: 287-290.  PubMed
3)  Akashi T, Fukuchi-Mizutani M, Aoki T, Ueyama Y, Yonekura-Sakakibara K, Tanaka Y, Kusumi T, Ayabe S  (1999)  Molecular cloning and biochemical characterization of a novel cytochrome P450, Flavone Synthase II, that catalyzes direct conversion of flavanones to flavones.  Plant Cell Physiol 40: 1182-1186.  PubMed
4)  Ayabe S-I, Akashi T, Aoki T  (2002)  Cloning of cDNAs encoding P450s in flavonoid/isoflavonoid pathway from elicited leguminous cell cultures.  Methods Enzymol 357: 360-369.

CYP93B2:   flavone synthase II, FNS II, (Gerbera).
Martens S, Forkmann G  (1999)  Cloning and expression of flavone synthase II from Gerbera hybrids.  Plant Journal 20: 611-618.  PubMed

CYP93B3:   flavone synthase II, FNS II (snapdragon, torenia).
1)  Akashi T, Fukuchi-Mizutani M, Aoki T, Ueyama Y, Yonekura-Sakakibara K, Tanaka Y, Kusumi T, Ayabe S  (1999)  Molecular cloning and biochemical characterization of a novel cytochrome P450, flavone synthase II, that catalyzes direct conversion of flavanones to flavones.  Plant Cell Physiol 40: 1182-1186.  PubMed
2)  Ueyama Y, Suzuki K-I, Fukuchi-Mizutani M, Fukui Y, Miyazaki K et al.  (2002)  Molecular and biochemical characterization of Torenia flavonoid 3'-hydroxylase and flavone synthase II and modification of flower color by modulating the expression of these genes.  Plant Science 163: 253-263.  

CYP93B4:   flavone synthase II, FNS II (snapdragon, torenia).
Akashi T, Fukuchi-Mizutani M, Aoki T, Ueyama Y, Yonekura-Sakakibara K, Tanaka Y, Kusumi T, Ayabe S  (1999)  Molecular cloning and biochemical characterization of a novel cytochrome P450, flavone synthase II, that catalyzes direct conversion of flavanones to flavones.  Plant Cell Physiol 40: 1182-1186.  PubMed

CYP93B6:   flavone synthase II (FSII), Chinese basil (Perilla frutescens).
Kitada C, Gong Z, Tanaka Y, Yamazaki M, Saito K  (2001)  Differential expression of two cytochrome P450s involved in the biosynthesis of flavones and anthocyanins in chemo-varietal forms of Perilla frutescens.  Plant Cell Physiol 42: 1338-1344.  PubMed


Comments? Questions?   email:  joan.krochko@nrc-cnrc.gc.ca   website:  P450s in Plants
Plant Biotechnology Institute, National Research Council, Saskatoon, Saskatchewan   CANADA   S7N0W9
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