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CYP88As


P450 Function Plant Species
CYP88A1 : ent-kaurenoic oxidase (KAO, Dwf3), GA biosynthesis maize
CYP88A2 ent-kaurenoic oxidase (KAO), GA biosynthesis pumpkin
CYP88A3 / A4 ent-kaurenoic oxidase (KAO), GA biosynthesis Arabidopsis
CYP88A6 ent-kaurenoic oxidase (KAO, NA), GA biosynthesis pea
CYP88A ent-kaurenoic oxidase (KAO), GA biosynthesis barley


CYP88A1:   GA biosynthesis, ent-kaurenoic oxidase (KAO, Dwarf3), corn (Zea mays).
1)  Winkler RG, Helentjaris T  (1995)  The maize Dwarf3 gene encodes a cytochrome P450-mediated early step in gibberellin biosynthesis.  Plant Cell 7: 1307-1317.  PubMed

CYP88A2:   GA biosynthesis, ent-kaurenoic oxidase (KAO), pumpkin (Cucurbita maxima), Accession No. AF212991.
Helliwell CA, Olive MR, Gebbie L, Forster R, Peacock WJ, Dennis ES  (2000)  Isolation of an ent-kaurene oxidase cDNA from Cucurbita maxima.  Aust J Plant Physiol 27: 1141-1149.  

CYP88A3:   CYP88A4:   ent-kaurenoic acid oxidase (KAO), GA biosynthesis.
Helliwell CA, Chandler PM, Poole A, Dennis, E.S., Peacock, W.J.  (2001)  The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway.  Proc Natl Acad Sci USA 98: 2065-2070.  PubMed

CYP88A6:   GA biosynthesis, ent-kaurenoic oxidase (KAO, NA), pea (Pisum sativum).
Davidson SE, Elliott RC, Helliwell CA, Poole AT, Reid JB  (2003)  The pea gene NA encodes ent-kaurenoic acid oxidase.  Plant Physiol 131: 335-344.  PubMed

CYP88A:   GA biosynthesis, ent-kaurenoic oxidase (KAO), barley (Hordeum vulgare).
Helliwell CA, Chandler PM, Poole A, Dennis ES, Peacock WJ  (2001)  The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway.  Proc Natl Acad Sci USA 98: 2065-2070.  PubMed


Comments? Questions?   email:  joan.krochko@nrc-cnrc.gc.ca   website:  P450s in Plants
Plant Biotechnology Institute, National Research Council, Saskatoon, Saskatchewan   CANADA   S7N0W9
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