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CYP79Ds


P450 Function Plant Species
CYP79D1 / D2 linamarin and lotaustralin biosynthesis cassava
CYP79D3 / D4 linamarin and lotaustralin biosynthesis lotus


CYP79D1:  CYP79D2:  biosynthesis of cyanogenic glucosides linamarin and lotaustralin, cassava (Manihot esculenta).
1)  Anderson MD, Busk PK, Svendsen I, Møller BL  (2000)  Cytochromes P-450 from cassava (Manihot esculenta Crantz) catalyzing the first steps in the biosynthesis of the cyanogenic glucosides linamarin and lotaustralin. Cloning, functional expression in Pichia pastoris, and substrate specificity of the isolated recombinant enzymes.  J Biol Chem 275: 1966-1975.  PubMed
2)  Mikkelsen MD, Halkier BA  (2003)  Metabolic engineering of valine- and isoleucine-derived glucosinolates in Arabidopsis expressing CYP79D2 from cassava.  Plant Physiol 131: 773-779.  PubMed
3)  Siritunga D, Sayre RT  (2003)  Generation of cyanogen-free transgenic cassava.  Planta 217: 367-373.  PubMed

CYP79D3:  CYP79D4:  biosynthesis of cyanogenic glucosides linamarin and lotaustralin, lotus (Lotus japonicus).
Forslund K, Morant M, Jørgensen B, Olsen CE, Asamizu E, Sato S, Tabata S, Bak S  (2004)  Biosynthesis of the nitrile glucosides rhodiocyanoside A and D and the cyanogenic glucosides lotaustralin and linamarin in Lotus japonicus.  Plant Physiol 135: 71-84.  PubMed


Comments? Questions?   email:  joan.krochko@nrc-cnrc.gc.ca   website:  P450s in Plants
Plant Biotechnology Institute, National Research Council, Saskatoon, Saskatchewan   CANADA   S7N0W9
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