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| P450 | Function | Plant Species |
|---|---|---|
| CYP51 : | obtusifolial 14-alpha-demethylase | sorghum, wheat |
| CYP51Nt | obtusifolial 14-alpha-demethylase | tobacco |
| CYP51G1 / G2 | obtusifolial 14-alpha-demethylase | Arabidopsis |
CYP51: obtusifolial 14-alpha-demethylase, sorghum, wheat.
1) Bak S, Kahn RA, Olsen CE, Halkier BA (1997) Cloning and expression in Escherichia coli of the obtusifoliol 14 alpha-demethylase of Sorghum bicolor (L.) Moench, a cytochrome P450 orthologous to the sterol 14 alpha-demethylases (CYP51) from fungi and mammals. Plant J 11: 191-201. PubMed
2) Cabello-Hurtado F, Taton M, Forthoffer N, Kahn R, Bak S, Rahier A, Werck-Reichhart D (1999) Optimized expression and catalytic properties of a wheat obtusifolial 14-alpha-demethylase (CYP51) expressed in yeast. Complementation of erg11Delta yeast mutants by plant CYP51. Eur J Biochem 262: 435-446. PubMed
3) Yoshida Y, Aoyama Y, Noshiro M, Gotoh O (2000) Sterol 14-demethylase P450 (CYP51) provides a breakthrough for the discussion on the evolution of cytochrome P450 gene superfamily. Biochem Biophys Res Commun 273: 799-804. PubMed
CYP51: obtusifolial 14-alpha-demethylase, tobacco.
Burger C, Rondet S, Benveniste P, Schaller H (2003) Virus-induced silencing of sterol biosynthesis genes; identification of a Nicotiana tabacum L. obtusifolial-14 alpha-demethylase (CYP51) by genetic manipulation of the sterol biosynthetic pathway in Nicotiana benthamania L. J Exp Bot 54: 1675-1683. PubMed
CYP51G1 (CYP51A2): CYP51G2 (CYP51A1): obtusifolial 14alpha-demethylase, Arabidopsis.
Kushiro M, Nakano T, Sato K, Yamagishi K, Asami T, Nakano A, Takatsuto S, Fujioka S, Ebizuka Y, Yoshida S (2001) Obtusifolial 14alpha-demethylase (CYP51) antisense Arabidopsis shows slow growth and long life. Biochem Biophys Res Commun 285: 98-104. PubMed